University of Washington School of Public Health

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Data Analyst Research Scientist 2 - Genetic Analysis Center/Biostatistics Department

Location: Seattle, WA
Full-time position
Closing Date: open until filled
Job #11468
Posted: May 19, 2017
Description:

The University of Washington’s Department of Biostatistics has an outstanding opportunity for a full time Data Analyst. 

The Genetic Analysis Center (GAC, www.biostat.washington.edu/research/centers/gac) in the Department of Biostatistics develops and applies statistical methods to genetic and health-related data with the aim of discovering how genetic variation contributes to human disease and well-being.   The genetic data include variations assayed by whole-genome sequencing or micro-arrays, and the health data cover a broad range of health-related traits, particularly complex diseases such as diabetes, asthma, atherosclerosis, and cancer; as well as responses to pharmaceuticals. The projects are funded by academic, non-profit and industrial institutions. A major current project is the Trans-Omics for Precision Medicine (TOPMed) Data Coordinating Center (www.nhlbiwgs.org).  

RESPONSIBILITIES: 
Primary responsibilities include management, quality control, and analysis of genetic and health- related phenotypic data.  Two current project examples:  (1) Using health-related survey and medical exam data from a variety of clinical research studies,  manage and organize the data; perform quality control analyses; identify common traits across diverse studies and perform transformations to harmonize those data; prepare harmonized data files and associated documentation.  (2) Using genetic data from micro-array or sequencing platforms, format data; perform quality control analyses; perform genotype-phenotype association analyses to identify genetic risk factors for disease-related phenotypes; prepare results files and associated documentation.  

These responsibilities involve the following activities: 

·  Work with GAC faculty and staff to develop goals and methods for data management and analysis. 
·  Construct, manipulate and interpret large and complex data sets. 
·  Identify problematic records in data sets and determine the best approach to handling them. 
·  Perform quality control on genotypic and phenotypic data. 
·  Program data transformations and analyses using the R statistical environment. 
·  Perform statistical data analysis of large data sets using parallel computing. 
·  Summarize and communicate results of analyses to GAC staff and clinical collaborators. 

Specific training will be provided for each of these activities, through working closely with more experienced team members. The GAC provides a highly collaborative environment in which team members share expertise and mentor new research staff.  Continuing education opportunities include attending workshops, short courses and conferences. 


REQUIREMENTS:

 

·  Bachelor’s degree in a scientific discipline such as statistics, genetics, mathematics, or computer science; and a minimum of two years of experience manipulating and analyzing data using a programming language (through classwork and/or employment). 

Additional  Requirements: 

·  Knowledge of, or willingness to learn, specialized data management and statistical analysis skills for projects relating to genetic health research. 
·  Excellent communication skills, oral and written  

Equivalent education/experience will substitute for all minimum qualifications except when there are legal requirements, such as a license/certification/registration.

DESIRED:

·  Background in genetics and statistics 
·  Experience in management, analysis and interpretation of scientific data sets. 
·  Experience in statistical software packages (e.g. R, SAS, STATA, S-Plus, SPSS), preferably R 
·  Experience with Linux or Unix systems 
·  Familiarity with reproducible research principles and tools

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