Professor, Env. and Occ. Health Sciences
319 Brotman Building (850 Republican St.)
Seattle, WA -
Dr. Rosenfeld studies nutrition and cardiovascular disease, role of nutrition in regulation of gene expression, lipid and lipoprotein metabolism, pathology of atherosclerosis. The research focuses on the pathogenesis of atherosclerosis with an emphasis on the role that macrophages play in this process. We are currently studying the heterogeneous nature of macrophage subpopulations by demonstrating differences in the stages of differentiation and activation of the cells. We are also studying the effects of inflammatory mediators such as oxidized LDL on the expression of growth factors and cytokines by isolated macrophage-derived foam cells and are attempting to expression clone potential foam cell specific neoantigens.
PhD Nutritional Science, University of Wisconsin, 1981
MS Cell Biology, University of Vermont, 1978
BA Biology, Grinnell College, 1975
In the News
GMOs: Tolerable or Pressing Health Risk?
The Olympian, 09/23/2013
Inhaling Auto Emissions Makes Good Cholesterol Go Bad
USA Today, 06/15/2013
When Good Cholesterol Turns Bad
Arteriosclerosis, Thrombosis, and Vascular Biology, 06/01/2013
Traffic Air Pollution Turns Good Cholesterol Bad
UW Today, 05/31/2013