Michael Rosenfeld

Professor, Env. and Occ. Health Sciences
Professor, Pathology

319 Brotman Building (850 Republican St.)
Box 358050

Seattle, WA -

206-543-1738
ssmjm@uw.edu

Research Interests

Dr. Rosenfeld studies nutrition and cardiovascular disease, role of nutrition in regulation of gene expression, lipid and lipoprotein metabolism, pathology of atherosclerosis. The research focuses on the pathogenesis of atherosclerosis with an emphasis on the role that macrophages play in this process. We are currently studying the heterogeneous nature of macrophage subpopulations by demonstrating differences in the stages of differentiation and activation of the cells. We are also studying the effects of inflammatory mediators such as oxidized LDL on the expression of growth factors and cytokines by isolated macrophage-derived foam cells and are attempting to expression clone potential foam cell specific neoantigens.

Education

PhD Nutritional Science, University of Wisconsin, 1981

MS Cell Biology, University of Vermont, 1978

BA Biology, Grinnell College, 1975

In the News

GMOs: Tolerable or Pressing Health Risk?
The Olympian, 09/23/2013

Inhaling Auto Emissions Makes Good Cholesterol Go Bad
USA Today, 06/15/2013

When Good Cholesterol Turns Bad
Arteriosclerosis, Thrombosis, and Vascular Biology, 06/01/2013

Traffic Air Pollution Turns Good Cholesterol Bad
UW Today, 05/31/2013