Pioneering methods to understand environmental exposures
Even as a doctoral student, Clarice stood out for her energy, mathematical ability and focus on methodological issues. Over her subsequent decades in public service, she has employed her methodological prowess to improve the design and analysis of epidemiological studies. Collaborating with physicians, epidemiologists and basic science researchers, Clarice has applied those innovations to studying the interplay among genetics and environmental exposures in complex diseases and conditions, including breast cancer, birth defects, infertility and pregnancy complications.
For her ongoing work on a major cohort study of more than 50,000 women who are sisters of a woman with breast cancer, Clarice won a National Institutes of Health Award of Merit. She is also a principal investigator on a family-based study of young-onset breast cancer. Clarice’s work has strengthened study designs and provided analysis toolkits for future public health researchers.
Affiliations: Principal investigator, Biostatistics & Computational Biology Branch, National Institute of Environmental Health Sciences; Adjunct Professor, Departments of Biostatistics and Epidemiology, University of North Carolina; Associate Editor, American Journal of Epidemiology